快乐彩|快乐彩走势图|快乐彩玩法技巧_百度搜狗

  1. Protein Tyrosine Kinase/RTK
  2. Ephrin Receptor

Ephrin Receptor

Ephrin receptors (Ephs) are a group of receptors that are activated in response to binding ephrin. Ephs form the largest known subfamily of receptor tyrosine kinases (RTKs). Both Ephs and their corresponding ephrin ligands are membrane-bound proteins that require direct cell-cell interactions for Eph receptor activation. Eph/ephrin signaling has been implicated in the regulation of a host of processes critical to embryonic development including axon guidance, formation of tissue boundaries, cell migration, and segmentation. Additionally, Eph/epherin signaling has recently been identified to play a critical role in the maintenance of several processes during adulthood including long-term potentiation, angiogenesis, and stem cell differentiation and cancer. The ability of Ephs and ephrins to mediate a variety of cell-cell interactions places the Eph/ephrin system in an ideal position to regulate a variety of different biological processes during embryonic development.

Ephrin Receptor 相关产品 (4):

Cat. No.Product NameEffectPurity
  • HY-18007
    ALW-II-41-27Inhibitor 99.38%
    ALW-II-41-27是 Eph家族酪氨酸激酶抑制剂,抑制Eph2的IC50为11 nM。
  • HY-13314
    TesevatinibInhibitor 99.21%
    Tesevatinib (XL-647) 是口服可用的多靶点酪氨酸激酶抑制剂; 抑制EGFRErbB2KDRFlt4EphB4激酶活性的IC50 值分别为 0.3,16,1.5,8.7,和1.4 nM。
  • HY-13258
    NVP-BHG712Inhibitor 99.51%
    NVP-BHG712是EphB4抑制剂,ED50为25 nM,对c-Raf,c-Src和c-Abl的IC50分别为0.395 μM,1.266 μM和1.667 μM。
  • HY-16265
    JI-101Inhibitor 99.95%
    JI-101是有口服活性的有抗癌活性的多靶点激酶抑制剂,可抑制 VEGFR2PDGFRβEphB4
Isoform Specific Products

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.