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  1. Anti-infection
  2. HBV

HBV

HBV (Hepatitis B virus), abbreviated HBV, is a species of the genus Orthohepadnavirus, which is likewise a part of the Hepadnaviridae family of viruses. HBV causes the disease hepatitis B. The hepatitis B virus is classified as the type species of the Orthohepadnavirus, which contains three other species: the Ground squirrel hepatitis virus, Woodchuck hepatitis virus, and theWoolly monkey hepatitis B virus. The genus is classified as part of the Hepadnaviridae family. HBV is divided into four major serotypes (adr, adw, ayr, ayw) based on antigenic epitopes present on its envelope proteins, and into eight genotypes (A–H) according to overall nucleotide sequence variation of the genome. The genotypes have a distinct geographical distribution and are used in tracing the evolution and transmission of the virus. Differences between genotypes affect the disease severity, course and likelihood of complications, and response to treatment and possibly vaccination.

HBV 相关产品 (24):

Cat. No.Product NameEffectPurity
  • HY-100029
    Bay 41-4109Inhibitor 98.92%
    BAY 41-4109是人乙型肝炎病毒 (HBV) 的有效抑制剂,IC50值为 53 nM。
  • HY-13623A
    Entecavir monohydrateInhibitor 99.95%
    Entecavir monohydrate(SQ 34676; BMS 200475)是有选择且有效地HBV抑制剂。在HepG2细胞中的EC50值为3.75 nM。
  • HY-13782
    Tenofovir Disoproxil FumarateInhibitor 99.80%
    Tenofovir Disoproxil Fumarate是用于治疗 HIV和慢性乙型肝炎核苷酸逆转录酶抑制剂。
  • HY-16468
    SqualamineInhibitor >98.0%
    Squalamine(MSI-1256)是具有广谱抗病毒活性化的化合物。
  • HY-108917
    MorphothiadinInhibitor 99.59%
    Morphothiadin 是野生型和阿德福韦耐药 HBV复制的有效抑制剂,其IC50 值为 12 nM。
  • HY-117650A
    RG7834Inhibitor >98.0%
    RG7834 (RO 7020322) 是一种高度选择性、可口服的 HBV 抑制剂,在 dHepaRG 细胞中,能够有效抑制 HBV 抗原 HBsAg,HBeAg 和 HBV DNA,IC50 值分别为 2.8,2.6 和 3.2 nM。
  • HY-13986
    MerimepodibInhibitor 98.22%
    Merimepodib是非竞争型,有口服活性的肌苷一磷酸脱氢酶 (IMPDH) 抑制剂,具有广谱抗病毒活性。
  • HY-B0255
    Adefovir dipivoxilInhibitor 98.50%
    Adefovir Dipivoxil可阻断HBV逆转录酶。
  • HY-112142
    AB-423Inhibitor 99.60%
    AB-423 是一种 HBV 衣壳组装抑制剂,在细胞中,能够抑制 HBV 复制,EC50/EC90 值分别为 0.08-0.27 μM/0.33-1.32 μM。
  • HY-13623
    EntecavirInhibitor 98.88%
    Entecavir(SQ 34676; BMS 200475)是有选择且有效地HBV抑制剂。在HepG2细胞中的EC50值为3.75 nM。
  • HY-101954
    InarigivirInhibitor 99.20%
    Inarigivir (ORI-9020;SB-9000) 是一种二核苷酸,可显着减少表达乙型肝炎病毒转基因小鼠的 HBV DNA。
  • HY-112564
    JNJ-632Inhibitor 99.36%
    JNJ-632 是一种乙型肝炎病毒 (HBV) 衣壳组装调节剂 (CAM)。
  • HY-107902
    RIG-1 modulator 1Inhibitor 98.81%
    RIG-1 modulator 1 是一种抗病毒化合物,可以用来治疗病毒性感染包括流感病毒,HBV,HCVHIV 来自专利 WO 2015172099 A1。
  • HY-100029A
    Bay 41-4109 racemateInhibitor 98.02%
    BAY 41-4109 racemate是BAY 41-4109的消旋体。BAY 41-4109是人乙型肝炎病毒HBV的有效抑制剂,IC50值为53 nM。
  • HY-B0955
    OxethazaineInhibitor 99.86%
    Oxethazaine是一种局部麻醉剂,在防止酸诱导的食管疼痛。
  • HY-B0766
    BicyclolInhibitor 99.97%
    Bicyclol(SY 801)是可口服的抗HBV,HCV化合物。
  • HY-B2116
    OsalmidInhibitor 99.80%
    Osalmid是核糖核苷酸还原酶小亚基M2(RRM2)的靶向化合物; 抑制核糖核苷酸还原酶活性的IC50值为8.23 μM。
  • HY-B0017
    TelbivudineInhibitor 99.87%
    Telbivudine是特异的HBV复制抑制剂。
  • HY-13859
    ClevudineInhibitor >98.0%
    Clevudine能抗乙肝病毒。
  • HY-13782A
    Tenofovir DisoproxilInhibitor >98.0%
    Tenofovir dsoproxil 是核苷酸逆转录酶抑制剂 (nucleotide reverse transcriptase inhibitor),用于治疗艾滋病和慢性乙型肝炎。
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