快乐彩|快乐彩走势图|快乐彩玩法技巧_百度搜狗

  1. Immunology/Inflammation
  2. IFNAR

IFNAR

The interferon-α/β receptor (IFNAR) is a receptor which binds type I interferons including interferon-α and -β. It is a heteromeric cell surface receptor composed of one chain with two subunits referred to as IFNAR1 and IFNAR2. Upon binding of type I IFNs, IFNAR activates the JAK-STAT signaling pathway. Interferon stimulation classically results in an anti-viral immune response. Type I IFNs share a common receptor consisting of two subunits, IFNAR1 and IFNAR2, which associate upon IFN binding. IFNAR2 is the major ligand binding component of the receptor complex, exhibiting nanomolar affinity to both IFNα and IFNβ subtypes. IFNAR1 and IFNAR2 belong to the class II helical cytokine receptor (hCR) family, which includes the receptor for type II IFN, tissue factor (TF), and IL10Rβ.

IFNAR 相关产品 (6):

Cat. No.Product NameEffectPurity
  • HY-100941
    CCCPInhibitor 99.83%
    CCCP是氧化磷酸化解偶联剂。
  • HY-12836A
    IFN alpha-IFNAR-IN-1 hydrochlorideInhibitor 99.76%
    IFN alpha-IFNAR-IN-1盐酸盐是IFN alpha和其受体IFNAR相互作用抑制剂,EC50值2-8 μM。
  • HY-107390A
    AX-024 hydrochlorideInhibitor 99.29%
    AX-024 hydrochloride 是一种细胞因子释放抑制剂,可以有效抑制白细胞介素-6 (IL-6),肿瘤坏死因子-α (TNFα),干扰素-γ (IFN-γ),IL-10IL-17A 的产生。
  • HY-107390
    AX-024Inhibitor >98.0%
    AX-024 是一种细胞因子释放抑制剂,可以有效抑制白细胞介素-6 (IL-6),肿瘤坏死因子-α (TNFα),干扰素-γ (IFN-γ),IL-10IL-17A 的产生。
  • HY-12836
    IFN alpha-IFNAR-IN-1Inhibitor
    IFN alpha-IFNAR-IN-1是IFN alpha和其受体IFNAR相互作用抑制剂,EC50值2-8uM。
  • HY-112189
    Interferon receptor inducer-1Agonist 98.49%
    Interferon receptor inducer-1 (compound 6) 是干扰素 (IFN) 受体的一个诱导剂。可用于治疗干扰素诱导参与的紊乱性疾病。
Isoform Specific Products

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.